Table 2.

Overall analysis representing SNPs from the Metabochip platform with P < 10−4 comparing prostate cancer cases (n = 871) versus controls (n = 906) from the NMHS

SNPChr.PositionOn gene/nearby genesEA/RAEAF controlsEAF casesORSEPN
CHR10:10474542110104745421CNNM2,a NT5C2, AS3MTA/G0.390.401.550.113.59 × 10−51,751
CHR6:1608363266160836326LPAL2,a SLC22A3, LPAC/T0.420.471.340.735.80 × 10−51,777
CHR11:8363462118363462STK33, LMO1, TRIM66C/T0.260.200.720.086.76 × 10−51,776
RS131115404111408792ELOVL6, ENPEP, PITX2A/G0.380.461.310.077.79 × 10−51,776
CHR12:10923182612109231826ATP2A2,a IFT81, ANAPC7T/C0.040.020.390.238.11 × 10−51,747

NOTE: Results adjusted for age and 10 principal components.

Abbreviations: EA, effect allele; EAF, effect allele frequency; RA, referent allele.

  • aSNP is on the gene.