Table 2.

Colorectal cancer incidence or mortality by asthma and hay fever status, in CPS-I, the CPS-II Mortality Cohort, and the CPS-II Nutrition Cohort

CPS-I Mortality, 1959—72CPS-II Mortality Cohort Mortality, 1982–2008CPS-II Nutrition Cohort, Incidence, 1992–2007
DeathsPerson-yearsRR (95% CI)aDeathsPerson-yearsRR (95% CI)aCasesPerson-yearsRR (95% CI)b
Asthma and hay fever status
 No asthma or hay fever4,9659,864,6151.00 (ref)11,97620,086,9921.00 (ref)2,9231,801,4291.00 (ref)
 Asthma only154287,4540.97 (0.82–1.14)302522,6591.01 (0.90–1.13)6544,2280.92 (0.72–1.18)
 Hay fever only417998,7500.97 (0.88–1.07)1,0782,354,6170.92 (0.86–0.98)307227,8780.95 (0.85–1.07)
 Hay fever and asthma108275,1170.90 (0.74–1.09)202529,5670.79 (0.69–0.91)7054,5250.90 (0.71–1.14)
  • aRR for colorectal cancer mortality adjusted for age, sex, race, education, BMI, physical activity, smoking, and aspirin use.

  • bRR for incident colorectal cancer, adjusted for age, sex, race, education, BMI, physical activity, smoking, aspirin use, and history of colorectal endoscopy.