Table 3.

CBMN outcomes for male cases and controls by smokinga and environmental exposureb

MalesCase (N = 500)P valueControl (N = 500)P value
BN-MN
 Overall3.52 ± 0.061.83 ± 0.05<0.001
 Smokinga
  Never smoker3.35 ± 0.171.85 ± 0.11
  Light smokers3.31 ± 0.171.92 ± 0.12
  Moderate smokers3.82 ± 0.131.65 ± 0.13
  Heavy smokers3.50 ± 0.091.85 ± 0.09
Ptrend = 0.07Ptrend = 0.38
Environmental exposureb
 Without exposure3.49 ± 0.110.931.87 ± 0.090.45
 With exposure3.50 ± 0.091.78 ± 0.07
BN-NPB
 Overall4.29 ± 0.050.98 ± 0.04<0.001
 Smokinga
  Never smoker4.12 ± 0.130.90 ± 0.08
  Light smokers4.48 ± 0.130.89 ± 0.08
  Moderate smokers4.24 ± 0.101.04 ± 0.09
  Heavy smokers4.30 ± 0.071.05 ± 0.07
Ptrend = 0.71Ptrend = 0.07
Environmental exposureb
 Without exposure4.30 ± 0.080.821.03 ± 0.090.22
 With at least 1 exposure4.27 ± 0.070.93 ± 0.05
  • aSmoking intensity, light smokers (0 < pack-years ≤ 20), moderate smokers (20 < pack-years ≤ 40), heavy smokers (40 < pack-years); means adjusted by age and environmental exposures.

  • bSelf-reported exposure to at least 1 of 7 environmental exposures (i.e., asbestos, fiberglass, wood dust, solvents, paints, exhaust, and bleach; means adjusted by age and smoking intensity.