Table 2.

Global CaSR association and individual SNP associations (per-allele OR and 95% CI) for lethal prostate cancera

SNP name (minor, major allele)Gene locationMinor allele frequency (controls)OR (95% CI)P
rs9820206(A,G)Intron0.250.86 (0.61–1.20)0.38
rs6438705(A,G)Intron0.180.65 (0.42–0.99)0.04
rs13083990(C,T)Downstream0.360.65 (0.47–0.89)0.008
rs4678173(A,C)Intron0.341.21 (0.92–1.60)0.17
rs1979869(C,T)Intron0.310.73 (0.51–1.03)0.08
rs2270916(C,T)Intron0.141.55 (1.09–2.20)0.01
rs16832787(A,G)Intron0.241.21 (0.87–1.69)0.26
rs2134223(A,G)Intron0.150.97 (0.66–1.44)0.89
rs4638910(G,T)Downstream0.140.94 (0.62–1.42)0.76
rs1501900(A,T)Intron0.211.15 (0.83–1.61)0.39
rs1393198(C,T)Intron0.130.94 (0.62–1.44)0.79
rs7613238(A,G)Intron0.501.10 (0.83–1.46)0.50
rs7637874(C,T)Intron0.251.21 (0.88–1.65)0.24
rs7648041(C,T)Promoter0.280.94 (0.69–1.29)0.70
rs7630625(A,G)Upstream0.391.00 (0.74–1.34)1.00
rs1801725(G,T)Exon0.160.70 (0.46–1.06)0.09
rs1042636(A,G)Exon0.080.78 (0.45–1.34)0.37
rs1801726(C,G)Exon0.041.41 (0.78–2.54)0.26
Kernel machine result0.04
  • a113 cases, 1,244 controls