Table 2.

MiRs that significantly (at P < 0.05) differentiate highest (T3) versus lowest (T1) consumers of quercetin-rich food intake, separately by histology

T1 mean ± SDT3 mean ± SDFold changeaPb
AD (n = 97)
hsa-miR-5020.085 ± 0.3530.202 ± 0.3501.1240.017
hsa-mir-5640.565 ± 0.2580.449 ± 0.2730.8900.030
hsa-miR-124a0.232 ± 0.4470.072 ± 0.4230.8520.044
hsa-miR-125a0.625 ± 0.7231.034 ± 0.7151.5050.045
SQ (n = 78)
hsa-miR-5100.283 ± 0.3610.147 ± 0.2950.8720.003
hsa-mir-6052.118 ± 0.8151.279 ± 0.7650.4320.004
hsa-miR-155−5.113 ± 1.071−4.777 ± 0.7841.3990.012
hsa-miR-373−0.005 ± 0.420−0.091 ± 0.3300.9170.014
hsa-miR-4530.597 ± 0.3240.491 ± 0.2110.8990.017
hsa-miR-5020.318 ± 0.3090.095 ± 0.2230.8010.017
hsa-miR-18b−2.621 ± 0.735−2.227 ± 0.7241.4830.020
hsa-miR-1831.160 ± 0.4950.779 ± 0.4700.6830.022
hsa-mir-5730.267 ± 0.3550.126 ± 0.4060.8690.024
hsa-miR-524a0.074 ± 0.259−0.082 ± 0.3410.8550.036
hsa-mir-612−0.171 ± 0.851−0.104 ± 0.7191.0690.042
hsa-miR-363a−0.076 ± 0.7780.124 ± 0.7031.2220.046
  • aFold change is the ratio (T3/T1) of geometric means (>1.0 indicates upregulation and < 1.0 downregulation).

  • bCoefficient P value from ANOVA model adjusted for age, sex, BMI, smoking status, non–quercetin-rich fruits and vegetables, red/processed meat, alcohol, and cigarette pack years.