Table 2.

Agents and studies with PFP associations and PFP frequency estimates

Agent—sorted by PFP frequencyNo. of studies w/PFP associationsNo. of PFP associationsTotal no. of associations mentioned in monograph (s)PFP frequency estimate
Talc, non-asbestiform (inhaled; refs. 14–16)111000.01
Spironolactone (17)11720.01
Surgical implants and other foreign bodies (18)
 Orthopedic implants of complex composition442300.02
 Silicone implants11350.03
Fluorides (in drinking water; refs. 19, 20)11360.03
Fluorescent lights (21)11250.04
Paracetamol (22)33700.04
Dimethylformamide (23, 24)11220.05
Saccharin (25)551020.05
Xylenes (26, 27)11160.06
Tea (28)10111480.07
Diazepam (29)23380.08
Doxylamine succinate (30)11130.08
Vitamin K substances (31)23370.08
Rock (stone) wool (32, 33)77720.10
Phenol (34, 35)23270.11
Toluene (36, 37)44380.11
Hair coloring products (personal use; refs. 38, 39)22322720.12
Electric fields (static and Extremely Low Frequency; ref. 40)911870.13
Hydrochloric acid (41)12150.13
Paint manufacture (occupational exposure; ref. 42)12160.13
Insulation glass wool (32, 33)45360.14
Mercury and inorganic mercury compounds (43)78530.15
Reserpine (44, 45)44260.15
Coal dust (46)9211350.16
Sulfur dioxide (47)67440.16
Lumber and sawmill industries (58, 49)68480.17
Madder root (50)23180.17
Methyl methacrylate (51)23180.17
Polychlorinated dibenzofurans (52)1160.17
Paper and pulp manufacture (53, 54)33180.17
Mineral oils (highly refined; refs. 55, 56)1214670.21
Leather tanning and processing (57, 58)78370.22
Cholesterol (blood; refs. 59, 60)1112500.24
Isonicotinic acid hydrazine (61, 62)13110.27
Crude oil (63)23100.30
Chlorinated drinking water (ref. 64; excluding studies on chlorination by-products)310280.36
Leather goods manufacture (65, 66)2250.40
Total1622132,0810.10

NOTE: PFP frequency estimates were calculated by dividing the number of PFP associations in the monograph(s) by the total number of associations explicitly mentioned in the respective monograph(s).