Table 1.

Baseline characteristics

Percentage of cases and controls
Childhood ALLChildhood AMLAdult ALLAdult AML
Cases (N = 2,199)Controls (N = 8,796)PaCases (N = 461)Controls (N = 1,844)PaCases (N = 1,050)Controls (N = 4,200)PaCases (N = 3,362)Controls (N = 13,448)Pa
Sex<0.00010.390.0010.11
 Male54.950.149.051.357.752.151.650.0
 Female45.149.951.048.742.347.948.450.0
Down syndrome<0.0001<0.0001<0.0001
 Yes1.80.111.10.050.80.0200.05
 No98.299.9988.999.9599.299.9810099.95
Other chromosomal aberrations0.0020.800.00080.003
 Yes0.30.050.20.20.40.020.20.06
 No99.799.9599.899.899.699.9899.899.94
Twinb0.030.590.160.90
 Yes3.02.22.82.42.51.81.71.7
 No97.097.897.297.697.598.298.398.3
  • aThe χ2 test (2-sided) of association between outcome and characteristic.

  • bIncluding triplets, quadruplets, etc.