Table 2.

Characteristics of 124 patients with PDAC analyzed from SEER TMA

Characteristic and component groupsGroup subtotals, N (%)aKLK7-positive tumors, N (%)bKLK7-negative tumors, N (%)bχ2PcMedian (quartiles) OSd, moLog-rank Pe
Age
 <5522 (18)12 (55)10 (45)0.67§10.5 (2–53)0.043§
 55–6431 (25)16 (52)15 (48)8 (3–16)
 65–7437 (30)24 (65)13 (35)9 (5–20)
 ≥7534 (27)18 (53)16 (47)3.5 (2–10)
Gender
 Male58 (47)37 (64)21 (36)0.12†5 (2–14)0.042†
 Female66 (53)33 (50)33 (50)9.5 (4–21)
Histopathologic grade
 Poorly differentiated20 (16)7 (35)13 (65)0.035†7.5 (2–13)0.10†
 Moderately/well-differentiated104 (84)63 (61)41 (39)6.5 (3–21)
Stage
 Localized62 (50)42 (68)20 (32)0.011†14 (7–28)<0.0001†
 With metastases, regional or distant62 (50)28 (45)34 (55)3 (1–6)
Disease group
 Resected primary48 (39)33 (69)15 (31)0.0002†21 (8.5–33.5)<0.0001†
 Unresectedf primary32 (26)23 (72)9 (28)6 (3–11)
 Unresectedf metastatic44 (35)14 (32)30 (68)3 (1–6.5)
  • aPercentage of 124 total.

  • bPercentage of the group subtotal.

  • cP value from the χ2 test with †1, †2, or §3 degrees of freedom.

  • dOS in months after diagnosis.

  • eP value from the log-rank test with †1, †2, or §3 degrees of freedom.

  • fUnresected or unknown.