Table 1.

Characteristics of advanced colorectal adenoma cases and controls in PLCO genotyped for this study

CharacteristicCases%Controls%p-value
No. of individuals1,3311,501
Gender0.75
 Female48136.155136.7
 Male85063.995063.3
Age at randomization (y)0.11
 55–5939529.750933.9
 60–6442331.845830.5
 65–6933024.834022.7
 70–7418313.819412.9
Race0.13
 White non-Hispanic1,23492.71,36891.1
 Other977.31338.9
Family history of colorectal cancer0.01
 Yes16913.214710.2
 No1,33186.81,29889.8
Alcohol consumption (g/d)0.06
 <148640.158041.5
 1–1539232.347934.3
 15–3013110.815811.3
 ≥3020316.818113.0
Prefortification dietary folate (mcg/d)0.0002
 <40082267.885060.8
 ≥40039032.254839.2
Postfortification dietary folate (mcg/d)<0.0001
 <40060449.858742.0
 ≥40060850.281158.0
Multivitamin use
 Ever14116.515615.10.42
 Never71483.587584.9
Body mass index (kg/m2)0.08
 <18.580.680.5
 18.5–2534826.344029.5
 25–3059745.268345.8
 ≥3036927.935924.1
Strenuous physical activity (h/wk)
 022518.618213.10.0002
 <121718.023116.6
 115512.817912.9
 218415.221815.7
 318415.221515.4
 ≥424320.136826.4
Smoking status<0.0001
 Never51038.471847.8
 Former19614.71057.0
 Current62446.967845.2

NOTE: May not sum to total number of participants due to missing covariate values.