Table 2.

HRs and 95% CIs for associations of NSAID intake and death from all causes and from breast cancer, WEB study (n = 1,024)a

Events (n)Crude HR (95% CI)Adjusted HR (95% CI)b
All cause mortality
Lifetime aspirin use
 Nonusers331.00 (reference)1.00 (reference)
 Ever-users1200.87 (0.59–1.28)0.82 (0.54–1.24)
Recent aspirin use
 Nonusers901.00 (reference)1.00 (reference)
 Users681.08 (0.79–1.48)0.92 (0.65–1.29)
Recent ibuprofen use
 Nonusers841.00 (reference)1.00 (reference)
 Users730.65 (0.48–0.89)0.71 (0.50–1.00)
Recent acetaminophen use
 Nonusers631.00 (reference)1.00 (reference)
 Users940.95 (0.69–1.30)0.94 (0.67–1.32)
Breast cancer mortality
Lifetime aspirin use
 Nonusers211.00 (reference)1.00 (reference)
 Ever-users710.81 (0.50–1.32)0.89 (0.53–1.52)
Recent aspirin use
 Nonusers581.00 (reference)1.00 (reference)
 Users370.90 (0.60–1.37)0.91 (0.58–1.41)
Recent ibuprofen use
 Nonusers421.00 (reference)1.00 (reference)
 Users530.96 (0.64–1.43)0.86 (0.55–1.34)
Recent acetaminophen use
 Nonusers361.00 (reference)1.00 (reference)
 Users591.05 (0.69–1.59)0.96 (0.62–1.49)
  • aBreast cancer cases diagnosed at stage 0 were excluded.

  • bAdjusted for age at diagnosis, race, education, body mass index, menopausal status, stage of breast cancer, estrogen receptor/progesterone receptor status, and other NSAIDs use.