Table 4.

Duration of diabetes mellitus and risk of colorectal cancer

Main analysis (shifted index date 3 years backwards in time)Analysis with original index date (no shift)
Diabetes duration (y)Cases/ControlsAdjusted ORa (95% CI)Cases/ControlsAdjusted ORa (95% CI)
<2178/1,1181.00 (ref)267/1,5021.00 (ref.)
2–5209/1,2881.04 (0.83–1.30)323/1,9670.90 (0.75–1.08)
5–10235/1,3541.11 (0.88–1.40)354/2,1610.85 (0.70–1.02)
>10298/1,7601.14 (0.90–1.46)450/2,7290.82 (0.67–1.01)
  • aAdjusted for BMI, smoking, prior use of metformin, sulfonylureas, insulin, aspirin, NSAID, and statins.