Table 2.

Effect of lifetime alcohol consumption on odds of developing cancer

SCCHN (all 5 sub sites combined)Oral cavity cancerOropharyngeal cancerOral cavity, oropharyngeal, hypopharyngeal cancer NOSHypopharyngeal cancerLaryngeal cancer
Lifetime alcohol Consumption, mLNo. of cases/controlsaAdjusted ORb (95% CI)No. of cases/controlsAdjusted ORb (95% CI)No. of cases/controlsAdjusted ORb (95% CI)No. of cases/controlsAdjusted ORb (95% CI)No. of cases/controlsAdjusted ORb (95% CI)No. of cases/controlsAdjusted ORb (95% CI)
Missing74/436/4322/4315/433/4328/43
0117/2801.00 (ref)22/2801.00 (ref)27/2801.00 (ref)23/2801.00 (ref)1/2801.00 (ref)44/2801.00 (ref)
>0–133,294209/4660.75 (0.56–1.02)19/4660.45 (0.23–0.89)69/4660.87 (0.53–1.44)48/4660.93 (0.54–1.62)5/4662.25 (0.26–19.84)68/4660.67 (0.42–1.08)
133,294–757,550318/3601.29 (0.95–1.76)41/3601.28 (0.68–2.41)94/3601.47 (0.89–2.45)51/3601.48 (0.83–2.64)9/3605.13 (0.61–43.04)123/3601.25 (0.78–2.00)
757,550+505/1733.22 (2.29–4.52)84/1735.34 (2.67–10.67)120/1733.47 (2.00–6.04)86/1734.49 (2.40–8.39)36/17328.74 (3.42–241.40)179/1732.26 (1.38–3.70)
  • aCases and controls do not sum to 1,227 and 1,325, respectively, because 4 cases and 3 controls are missing information on duration of cigarette smoking.

  • bConditional logistic regression models for estimating main effects of categorized lifetime ethanol consumption were conditioned on sex, race, and age category, and adjusted for continuous smoking duration rounded to whole years.