Table 1.

Pearson r correlations of toxicant exposure and smoking machine yield obtained for CO yield, CO dose, and smoke volume

CO yieldCO doseSmoke volume
Puff topography
Smoke volume0.92a0.94a1
Blood exposure
COHb0.79a0.98a0.90a
CO dose0.82a10.94a
Nicotine concentration0.37b0.44b0.41b
Nicotine dose0.36b0.43b0.41b
Normalized nicotine dose0.49b0.71a0.79a
Machine yields
Tar0.82a0.64a0.76a
CO10.82a0.92a
NO0.97a0.93a0.98a
Nicotine0.41b0.29 (n.s.)0.36b
Nicotine (normalized)0.57b0.52c0.65a
PAH
Fluoranthene0.65a0.48a0.59a
Pyrene0.67a0.51a0.63a
Benzo[a]anthracene0.72a0.50a0.60a
Chrysene0.60a0.48a0.56a
Benzo[b + k]fluoranthenes0.60a0.43a0.54a
Benzo[a]pyrene0.56a0.24a0.33a
Benzo[g,h,i]perylene0.58a0.42a0.42a
Indeno[1,2,3-cd]pyrene0.57a0.40a0.42a
Aldehydes
Formaldehyde0.62a0.92a0.84a
Acetaldehyde0.91a0.87a0.94a
Acetone0.85a0.77a0.87a
Propionaldehyde0.82a0.82a0.86a
Methacrolein0.71a0.57a0.65a
Nicotine content in product
Nicotine in product–0.069 (n.s.)0.25 (n.s.)0.23 (n.s.)

NOTE: Dose = blood concentration × estimated blood volume. Normalized nicotine dose = nicotine dose/nicotine in tobacco product.

Abbreviation: n.s., not significant.