Table 2.

Levels of long-term follow-up carea for childhood cancer survivors

Risk of late effectsProposed levels of follow-up care
Low▪ Postal or telephone follow-up every 1 to 2 years.
Surgery only; low-risk chemotherapy (excluding alkylators, anthracyclines, bleomycin, and epipodophyllotoxins)▪ Single visit with cancer center long-term follow-up program followed by ongoing monitoring by primary care provider, according to follow-up plan established by cancer center.
Moderate▪ Follow-up every 1 to 2 years with nurse or primary care physician.
Other than high/low risk▪ Initial follow-up at cancer center for 5 to 10 years, followed by transition to primary care provider, who carries out ongoing monitoring according to follow-up plan established by cancer center.
High▪ Ongoing annual follow-up in specialized long-term follow-up program at cancer center.
Hematopoietic cell transplant; high-dose anthracyclines or alkylating agents; radiation ≥24 Gy

Adapted from references 27–31.

  • aLong-term follow-up begins 2 years following completion of therapy.