Table 4.

Associations of serum levels of SP-D and KL-6 with chest X-ray scarring among controls

 No scarring nAny scarringUnilateral scarringBilateral scarring
nORa (95% CI)nORa(95% CI)nORa(95% CI)
SP-D, ng/mL
 17.1–71.7135391.00261.00131.00
 71.8–105.3131521.36 (0.84–2.22)351.36 (0.77–2.40)171.30 (0.60–2.80)
 105.4–143.8136481.31 (0.80–2.15)331.34 (0.75–2.39)151.23 (0.56–2.73)
 143.9–506.6127641.67 (1.04–2.70)321.22 (0.68–2.19)322.51 (1.24–5.09)
Ptrend = 0.05Ptrend = 0.68Ptrend = 0.005
KL-6, μg/mL
 178.8–231.0135471.00291.00181.00
 231.1–325.7135561.14 (0.72–1.82)351.16 (0.67–2.03)211.13 (0.57–2.24)
 325.8–465.7132531.16 (0.72–1.84)341.20 (0.69–2.08)191.09 (0.54–2.18)
 465.8–4,225.9127471.04 (0.64–1.68)281.00 (0.56–1.78)191.07 (0.53–2.17)
Ptrend = 0.99Ptrend = 0.86Ptrend = 0.93
  • aModels were adjusted for age, sex, smoking status, time since quitting, cumulative smoking, and randomization year.