Table 3.

Adjusted HRs and 95% CIs of demographic, personal, tumor and treatment factors in FN women after a breast cancer diagnosis (stages I, II, and III–IV)

FactorsHR (95% CI)
Stage IStage IIStages III and IV
Distance to RCC
 Close1.001.001.00
 Moderate0.61 (0.20–1.84)0.90 (0.34–2.38)1.15 (0.51–2.56)
 Far0.76 (0.24–2.38)1.49 (0.61–3.66)1.19 (0.50–2.81)
BMI
 Normal weight (BMI <25 kg/m2)1.001.001.00
 Overweight (BMI ≥25 to <30 kg/m2)1.65 (0.48–5.69)0.48 (0.15–1.60)0.98 (0.28–3.36)
 Obese (BMI ≥30 kg/m2)1.25 (0.35–4.51)0.48 (0.16–1.46)1.63 (0.53–4.99)
Smoking status
 Never smoker1.001.001.00
 Ever smoker1.63 (0.42–6.37)0.90 (0.41–1.99)0.90 (0.37–2.19)
Comorbidity
 No1.001.001.00
 Other4.65 (1.39–15.53)a1.57 (0.45–5.54)1.90 (0.68–5.26)
 Diabetes5.49 (1.69–17.90)b1.77 (0.80–3.92)3.08 (1.26–7.50)a
Family history
 No1.001.001.00
 Yes0.64 (0.20–2.02)0.50 (0.20–1.22)1.80 (0.87–3.74)
Method of detection
 Nonscreen detected1.001.001.00
 Screen detected1.11 (0.43–2.87)0.79 (0.29–2.12)0.56 (0.13–2.34)
Estrogen/progesterone receptor status
 Neither positive1.001.001.00
 Either positive0.41 (0.16–1·04)0.75 (0.37–1.53)0.68 (0.34–1.30)
Stage- and age-appropriate treatment
 Yes1.001.001.00
 No1.33 (0.38–4.64)0.83 (0.38–1.80)1.95 (0.97–3.92)

NOTE: Unknown and unstageable data are not included in the statistical tests. Models were adjusted for age at diagnosis and period of diagnosis.