Table 2.

ORs and 95% CIs comparing HPV seropositivity in adenoma and hyperplastic polyp cases to controls, stratified by sex: Group Health members, 1998–2003

 Women (N = 261)
Controls (n = 138)Adenomas (n = 78)Hyperplastic polyps (n = 45)
Pos, n (%)Pos, n (%)Crude ORAdjusteda ORPos, n (%)Crude ORAdjusteda OR
Any type61 (46)29 (37)0.68 (0.39–1.21)0.78 (0.43–1.41)18 (40)0.77 (0.39–1.53)0.88 (0.43–1.80)
HPV-1635 (25)11 (14)0.48 (0.23–1.02)0.58 (0.27–1.24)12 (27)1.07 (0.50–2.30)1.32 (0.59–2.96)
HPV-1818 (13)5 (6)0.46 (0.16–1.28)0.60 (0.21–1.75)0 (0)0 (0–0.65)N/Ab
HPV-16 or -1843 (31)15 (19)0.53 (0.27–1.03)0.63 (0.31–1.26)12 (27)0.80 (0.37–1.71)0.97 (0.44–2.13)
HPV-3118 (13)8 (10)0.76 (0.31–1.84)0.90 (0.36–2.25)3 (7)0.48 (0.13–1.70)0.65 (0.18–2.40)
HPV-3315 (11)3 (4)0.33 (0.09–1.17)0.31 (0.09–1.14)2 (4)0.38 (0.08–1.74)0.31 (0.06–1.42)
HPV-359 (7)5 (6)0.98 (0.32–3.04)1.14 (0.35–3.74)3 (7)1.02 (0.26–3.96)1.31 (0.31–5.47)
HPV-396 (4)1 (1)0.29 (0.03–2.42)0.41 (0.05–3.71)1 (2)0.50 (0.06–4.27)0.86 (0.09–8.01)
HPV-453 (2)1 (1)0.59 (0.06–5.72)0.57 (0.06–5.72)0 (0)0 (0–4.38)N/Ab
HPV-528 (6)2 (3)0.43 (0.09–2.07)0.42 (0.08–2.06)1 (2)0.37 (0.04–3.04)0.41 (0.05–3.50)
HPV-589 (7)5 (6)0.98 (0.32–3.04)1.05 (0.32–3.45)0 (0)0 (0–1.42)N/Ab
HPV-681 (1)0 (0)0 (0–3.56)N/Ab0 (0)0 (0–6.71)N/Ab
Men (N = 206)
Controls (n = 93)Adenomas (n = 73)Hyperplastic polyps (n = 40)
Pos, n (%)Pos, n (%)Crude ORAdjustedaORPos, n (%)Crude ORAdjustedaOR
Any type26 (28)20 (28)0.97 (0.49–1.93)1.02 (0.48–2.16)14 (35)1.39 (0.63–3.06)1.44 (0.61–3.41)
HPV-1612 (13)10 (14)1.07 (0.43–2.64)1.01 (0.39–2.59)6 (15)1.19 (0.41–3.43)1.22 (0.40–3.66)
HPV-183 (3)2 (3)0.84 (0.13–5.20)0.87 (0.13–5.75)4 (10)3.33 (0.71–15.64)3.19 (0.63–16.28)
HPV-16 or -1813 (14)12 (16)1.21 (0.52–2.84)1.20 (0.49–2.95)7 (18)1.31 (0.48–3.56)1.36 (0.48–3.89)
HPV-316 (6)6 (8)1.30 (0.40–4.21)1.55 (0.45–5.30)5 (13)2.07 (0.59–7.23)2.20 (0.59–8.20)
HPV-333 (3)6 (8)2.69 (0.65–11.13)2.56 (0.59–11.03)6 (15)5.29 (1.25–22.37)5.23 (1.17–23.24)
HPV-352 (2)2 (3)1.28 (0.18–9.32)1.04 (0.14–7.93)6 (15)8.03 (1.55–41.73)6.74 (1.24–36.57)
HPV-391 (1)1 (1)1.28 (0.08–20.78)0.98 (0.06–16.41)1 (3)2.36 (0.14–38.68)1.76 (0.10–30.52)
HPV-450 (0)2 (3)∞ (0.61–∞)N/Ac1 (3)∞ (0.03–∞)N/Ac
HPV-524 (4)4 (5)1.29 (0.31–5.34)1.43 (0.33–6.23)3 (8)1.80 (0.38–8.46)1.78 (0.35–9.12)
HPV-582 (2)2 (3)1.28 (0.18–9.32)1.24 (0.14–10.81)0 (0)0 (0–4.75)N/Ab
HPV-680 (0)0 (0)N/AdN/Ad0 (0)N/AdN/Ad
  • aAdjusted for age, race, smoking status, BMI, alcohol consumption, and education.

  • bZero cases seropositive, only crude OR (95% CI) can be calculated.

  • cZero controls seropositive, only crude OR (95% CI) can be calculated.

  • dZero cases and 0 controls seropositive.