Table 2.

Multivariate HR and 95% CIs after a breast cancer diagnosis associated with FN status and important factors by stage at diagnosis (stages I, II, and III–IV)

Adjusted modelaHR (95% CI)
Stage IStage IIStages III–IV
FN status
 Non-FN1.001.001.00
 FN3.10 (1.39–6.88)b0.88 (0.50–1.54)1.44 (0.80–2.58)
Distance to RCC
 Close1.001.001.00
 Moderate0.92 (0.42–2.03)0.80 (0.41–1.54)0.36 (0.16–0.83)c
 Far0.67 (0.27–1.68)1.72 (0.85–3.48)0.84 (0.43–1.64)
BMI
 Normal (BMI <25 kg/m2)1.001.001.00
 Overweight (BMI ≥25 to <30 kg/m2)1.04 (0.45–2.39)0.76 (0.40–1.42)0.69 (0.34–1.41)
 Obese (BMI ≥30 kg/m2)0.69 (0.28–1.69)0.60 (0.31–1.15)1.16 (0.63–2.14)
Smoking status
 Never smoker1.001.001.00
 Ever smoker1.51 (0.73–3.15)1.07 (0.65–1.78)0.85 (0.47–1.55)
Comorbidity
 No1.001.001.00
 Other3.87 (1.59–9.43)b1.68 (0.82–3.45)2.28 (1.06–4.89)c
 Diabetes6.53 (2.71–15.77)d1.26 (0.62–2.55)1.48 (0.69–3.18)

NOTE: Unknown and unstageable data are not included in the statistical tests.

  • aModels were adjusted for age at diagnosis, period at diagnosis, RCC, FN status, distance to RCC, BMI, smoking status, and comorbidity.

  • bP ≤ 0.05.

  • cP ≤ 0.01.

  • dP ≤ 0.0001.