Table 2

Association of childhood ALL with paternal and maternal occupational exposure to chemicals, dusts, and fumesa

Any timePreconceptionDuring pregnancyPostnatal
Case/controlOR (95% CI)Case/controlOR (95% CI)Case/controlOR (95% CI)Case/controlOR (95% CI)
Paternal exposure to
Solvents151 /3821.0 (0.8–1.3)138 /3591.0 (0.8–1.2)113 /2921.0 (0.8–1.3)111 /3031.0 (0.8–1.2)
Paints or lacquers157 /3691.1 (0.9–1.4)147 /3451.1 (0.9–1.4)129 /2981.1 (0.9–1.4)115 /2961.0 (0.8–1.3)
Oil products180 /4121.1 (0.9–1.3)167 /3841.1 (0.9–1.3)151 /3251.2 (0.9–1.5)137 /3321.0 (0.8–1.3)
Plastic or resin fumes60 /1321.1 (0.8–1.5)54 /1161.1 (0.8–1.6)43 /961.1 (0.7–1.6)41 /1011.0 (0.7–1.4)
Industrial dusts160 /3531.3 (1.0–1.6)143 /3211.3 (1.0–1.6)123 /2811.2 (1.0–1.6)119 /2821.2 (0.9–1.5)
Metal melting109 /2860.9 (0.7–1.2)99 /2620.9 (0.7–1.2)81 /2071.0 (0.8–1.3)77 /2150.9 (0.7–1.2)
Maternal exposure to
Solvents66 /1471.1 (0.8–1.6)62 /1231.2 (0.9–1.7)36 /731.3 (0.8–1.9)22 /591.1 (0.6–1.8)
Paints or lacquers54 /771.8 (1.2–2.6)45 /711.6 (1.1–2.4)32 /422.0 (1.2–3.3)18 /441.0 (0.6–1.8)
Oil products25 /501.3 (0.8–2.2)25 /441.5 (0.9–2.5)18 /311.6 (0.8–2.9)9 /251.1 (0.5–2.4)
Plastic or resin fumes16 /291.3 (0.7–2.5)14 /221.5 (0.7–3.0)10 /161.5 (0.6–3.5)4 /150.8 (0.3–2.5)
Industrial dusts24 /531.3 (0.8–2.2)20 /411.4 (0.8–2.5)15 /331.3 (0.7–2.4)11 /301.1 (0.5–2.2)
Metal melting26 /770.9 (0.6–1.5)23 /631.0 (0.6–1.7)14 /430.9 (0.5–1.7)9 /290.9 (0.4–2.0)
  • a ORs and respective 95% CIs derived from logistic regression analysis stratified for gender, age, and year of birth and adjusted for socioeconomic status (high or other) and degree of urbanization (urban, mixed, or rural).