Table 3

Serum GST-α concentration and serum GST (NBD-C1) activity: The ratio between response to basal and vegetable-supplemented diets

BasalaBrassica/BasalbAllium/BasalbApiaceous/Basalb
GST-α, pg/ml3,605 ± 3781.13 ± 0.07c1.02 ± 0.060.95 ± 0.06
GSTM1-null3,041 ± 4171.26 ± 0.10 c1.07 ± 0.091.00 ± 0.08
Men (n = 10) d3,498 ± 7351.16 ± 0.141.05 ± 0.140.93 ± 0.12
Women (n = 15)d2,644 ± 4491.38 ± 0.14c1.09 ± 0.111.08 ± 0.11
GSTM1+4,316 ± 6910.96 ± 0.090.95 ± 0.090.90 ± 0.08
Men (n = 11)d6,568 ± 1,3140.90 ± 0.110.95 ± 0.110.78 ± 0.09*
Women (n = 7)2,836 ± 7091.02 ± 0.150.96 ± 0.141.04 ± 0.15
GST (NBD-C1), units/l75.9 ± 2.71.03 ± 0.021.02 ± 0.021.01 ± 0.02
GSTM1-null70.1 ± 3.21.07 ± 0.03c1.04 ± 0.031.05 ± 0.03
Men71.5 ± 5.01.06 ± 0.051.08 ± 0.051.08 ± 0.05
Women68.7 ± 3.91.08 ± 0.04c1.00 ± 0.041.03 ± 0.04
GSTM1+82.3 ± 4.10.98 ± 0.040.99 ± 0.030.97 ± 0.03
Men87.4 ± 5.81.00 ± 0.041.01 ± 0.040.94 ± 0.04
Women77.5 ± 6.20.96 ± 0.050.97 ± 0.050.99 ± 0.05
  • a LS-mean ± SE, adjusted for sex, GSTM1 genotype, feeding period, and sampling day.

  • b The statistical analyses for GST-α and GST (NBD-C1) activity were done on the log-transformed variables. The results presented are the values after back-transformation. The difference of the log-transformed means after back-transformation is the ratio of the LS-means on the original scale.

  • c Significant comparison between vegetable diet and basal diet (P < 0.05).

  • d One GSTM1-null male and one GSTM1-null female did not complete the basal diet; one GSTM1+ male did not complete the brassica and allium diets; and one GSTM1-null male did not complete the apiaceous diet.