Table 6

ORs for combinations of COMT and GST genotypes and breast cancer

GenotypeCases/controlsORa (95% CI)
COMTGSTM1
HH or HLPresent299 /273Referent
LL Present70 /840.8 (0.5–1.1)
HH or HLNull198 /2040.8 (0.6–1.1)
LL Null54 /540.9 (0.6–1.3)
Missing67 /48
GenotypeCases/controlsORa (95% CI)
COMTGSTT1
HH or HLPresent418 /400Referent
LL Present103 /1170.8 (0.6–1.1)
HH or HLNull87 /830.9 (0.7–1.3)
LL Null17 /190.9 (0.4–1.7)
Missing63 /44
GenotypeCases/controlsORa (95% CI)
COMTGSTP1
HH or HLIle/Ile181 /143Referent
LL Ile/Ile48 /470.8 (0.5–1.3)
HH or HLIle/Val or Val/Val287 /3040.8 (0.6–1.0)
LL Ile/Val or Val/Val72 /820.7 (0.5–1.0)
Missing100 /87
  • a Adjusted for age and race.