Table 4

Risk of erythroplakia and interactions between chewing, smoking, and drinking

CasesControlsCrude OR (95% CI)Adjusted ORa (95% CI)Further adjusted ORb (95% CI)
Chewing/Smoking
No/No326,7311.01.01.0
No/Yes67,6427.0 (1.7–28.0)5.6 (1.3–24.0)5.8 (1.3–25.3)
Yes/No548,83654.5 (17.0–174.2)43.0 (13.2–140.0)43.3 (13.3–141.1)
Yes/Yes374,56472.2 (22.3–234.4)53.6 (15.2–188.5)50.1 (14.1–178.4)
Chewing/Drinking
No/No630,5661.01.01.0
No/Yes33,8074.0 (1.0–16.1)3.8 (0.9–16.3)3.7 (0.9–16.1)
Yes/No5610,23527.9 (12.0–64.7)22.6 (9.6–53.5)22.7 (9.6–53.7)
Yes/Yes353,16556.3 (23.7–134.0)43.6 (16.4–116.1)43.1 (16.1–115.3)
Drinking/Smoking
No/No4834,4721.01.01.0
No/Yes146,3291.6 (0.9–2.9)2.2 (1.0–4.8)2.1 (1.0–4.4)
Yes/No91,0955.9 (2.9–12.1)8.1 (3.0–21.9)4.8 (1.8–13.1)
Yes/Yes295,8773.5 (2.2–5.6)5.9 (2.5–13.7)4.7 (2.0–10.6)
  • a OR adjusted for age (continuous), sex (M/F), education (categories from Table 2<$REFLINK> ), and BMI (continuous, kg/m2).

  • b In addition to the adjustment of age, sex, education, and BMI, for the model to assess the interactions between chewing and smoking, drinking was further adjusted; for the model to assess the interactions between chewing and drinking, smoking was further adjusted; for the model to assess the interactions between drinking and smoking, chewing was further adjusted.