ORs with 95% CIs of developing endometrial cancer according to quartiles of serum levels of specific PCB congenersa
Congener | Modelb | OR (95% CI) | P for trendc | ||||||
---|---|---|---|---|---|---|---|---|---|
Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | ||||||
CB 105 | Age-adjusted | 1.0 | 1.4 (0.7–2.6) | 1.2 (0.6–2.4) | 1.2 (0.6–2.3) | 0.69 | |||
Multivariate | 1.0 | 1.2 (0.6–2.3) | 1.0 (0.5–1.8) | 0.8 (0.4–1.6) | 0.42 | ||||
CB 118 | Age-adjusted | 1.0 | 1.7 (0.9–3.3) | 1.6 (0.8–3.1) | 1.9 (1.0–3.7) | 0.11 | |||
Multivariate | 1.0 | 0.6 (0.8–3.0) | 1.2 (0.6–2.4) | 1.4 (0.7–2.8) | 0.58 | ||||
CB 138 | Age-adjusted | 1.0 | 0.9 (0.5–1.8) | 1.2 (0.7–2.2) | 1.0 (0.6–1.9) | 0.74 | |||
Multivariate | 1.0 | 0.8 (0.4–1.6) | 1.2 (0.6–2.2) | 0.9 (0.5–1.7) | 0.95 | ||||
CB 153 | Age-adjusted | 1.0 | 0.9 (0.5–1.7) | 1.1 (0.6–2.0) | 0.8 (0.4–1.4) | 0.58 | |||
Multivariate | 1.0 | 0.9 (0.5–1.7) | 1.2 (0.6–2.2) | 0.9 (0.5–1.7) | 0.94 | ||||
CB 156 | Age-adjusted | 1.0 | 1.4 (0.8–2.5) | 1.1 (0.6–2.0) | 0.7 (0.4–1.3) | 0.18 | |||
Multivariate | 1.0 | 1.6 (0.8–2.9) | 1.4 (0.7–2.6) | 1.0 (0.5–2.0) | 0.90 | ||||
CB 167 | Age-adjusted | 1.0 | 2.2 (1.1–4.2) | 1.6 (0.8–3.2) | 2.0 (1.0–4.1) | 0.19 | |||
Multivariate | 1.0 | 2.0 (1.0–3.9) | 1.4 (0.7–2.9) | 1.9 (0.9–3.9) | 0.24 | ||||
CB 180 | Age-adjusted | 1.0 | 0.9 (0.5–1.6) | 0.8 (0.5–1.5) | 0.7 (0.4–1.4) | 0.32 | |||
Multivariate | 1.0 | 1.1 (0.6–2.0) | 1.1 (0.6–2.2) | 1.2 (0.6–2.2) | 0.67 |
a Median values for quartile 1 (cases/controls); quartile 4 (cases/controls), in ng/g lipid: CB 105, 1/1; 11.5/10.7; CB 118, 25.2/20.3; 73.4/70.9; CB 138, 67/59.1; 154/165; CB 153, 157/143; 342.5/351; CB 156, 12.9/12; 28.3/27.5; CB 167, 5/4.6; 14.7/15; CB 180, 108.5/103; 224.5/227.
b Multivariate adjusted for age and BMI.
c Tests for trend were performed by assigning consecutive integers to levels of categorized variables.