ORs with 95% CIs of developing endometrial cancer according to quartilesa of serum organochlorine pesticide levels
Compound | Modelb | OR (95% CI) | P for trendc | ||||||
---|---|---|---|---|---|---|---|---|---|
Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | ||||||
p,p′-DDT | Age-adjusted | 1.0 | 1.3 (0.7–2.5) | 1.1 (0.6–2.2) | 1.8 (1.0–3.4) | 0.08 | |||
Multivariate | 1.0 | 1.1 (0.6–2.2) | 0.8 (0.4–1.6) | 1.1 (0.5–2.1) | 0.95 | ||||
p,p′-DDE | Age-adjusted | 1.0 | 1.0 (0.6–2.0) | 1.4 (0.7–2.5) | 1.4 (0.8–2.6) | 0.17 | |||
Multivariate | 1.0 | 0.9 (0.5–1.8) | 1.1 (0.6–2.0) | 1.0 (0.6–2.0) | 0.78 | ||||
HCB | Age-adjusted | 1.0 | 1.3 (0.7–2.4) | 1.1 (0.6–2.1) | 1.1 (0.6–2.2) | 0.95 | |||
Multivariate | 1.0 | 1.2 (0.6–2.2) | 1.0 (0.5–1.9) | 1.0 (0.5–1.9) | 0.76 | ||||
β-HCH | Age-adjusted | 1.0 | 1.0 (0.5–2.0) | 1.4 (0.7–2.7) | 1.3 (0.7–2.6) | 0.29 | |||
Multivariate | 1.0 | 0.8 (0.4–1.5) | 1.0 (0.5–2.0) | 0.9 (0.5–1.9) | 0.87 | ||||
Oxychlordane | Age-adjusted | 1.0 | 1.3 (0.7–2.6) | 1.2 (0.6–2.4) | 1.8 (0.9–3.4) | 0.12 | |||
Multivariate | 1.0 | 1.1 (0.6–2.2) | 1.0 (0.5–2.0) | 1.4 (0.7–2.8) | 0.33 | ||||
trans-Nonachlor | Age-adjusted | 1.0 | 1.4 (0.7–2.7) | 1.6 (0.8–3.1) | 1.4 (0.7–2.8) | 0.31 | |||
Multivariate | 1.0 | 1.2 (0.6–2.3) | 1.3 (0.7–2.7) | 1.2 (0.6–2.5) | 0.56 |
a Median values for quartile 1 (cases/controls); quartile 4 (cases/controls), in ng/g lipid: p,p′-DDT, 6.3/4.8; 37.3/34; p,p′-DDE, 209.5/181; 1072/1165; HCB, 40.8/40.2; 109.5/94.2; β-HCH, 26/21.9; 100/98.4; oxychlordane, 6.7/6.9; 24/22.9; trans-nonachlor, 12.4/13; 40.4/39.1.
b Multivariate adjusted for age and BMI.
c Tests for trend were performed by assigning consecutive integers to levels of categorized variables.