Table 4

RRs and 95% CIs for non-Hodgkin’s lymphoma according to the quintile group for intake of vitamins A, C, and E in 1980

Quintile of nutrient intakeaQ5 95% CIdP for trende
12345
Preformed vitamin A from food and supplements
No. of cases3739413547
Intake (IU/day)85418652711582510,415
RR
Age-adjusted1.000.971.010.851.100.72–1.700.68
Multivariate-adjustedb1.000.991.000.891.080.70–1.670.74
Multivariate-adjustedc1.000.981.010.931.190.77–1.850.38
Preformed vitamin A, food only
No. of cases3538315540
Intake (IU/day)7191572205927095466
RR
Age-adjusted1.001.000.821.390.970.62–1.520.99
Multivariate-adjustedb1.001.070.821.380.990.62–1.560.96
Multivariate-adjustedc1.001.090.811.391.080.68–1.710.63
Vitamin A from food and supplements
No. of cases4339323649
Intake (IU/day)5131804411,10914,82622,418
RR
Age-adjusted1.000.840.670.720.950.63–1.430.94
Multivariate-adjustedb1.000.860.700.740.970.64–1.470.92
Multivariate-adjustedc1.000.890.750.831.190.78–1.830.28
Vitamin A, food only
No. of cases4441353247
Intake (IU/day)47256962932212,39417,912
RR
Age-adjusted1.000.860.710.620.860.57–1.290.51
Multivariate-adjustedb1.000.870.720.650.890.58–1.340.56
Multivariate-adjustedc1.000.900.770.711.080.70–1.660.73
Vitamin C from food and supplements
No. of cases3451303450
Intake (mg/day)70113154228704
RR
Age-adjusted1.001.430.810.901.270.82–1.980.30
Multivariate-adjustedb1.001.470.840.931.300.84–2.020.31
Multivariate-adjustedc1.001.570.961.171.601.02–2.510.07
Vitamin C, food only
No. of cases3648443932
Intake (mg/day)6194121152209
RR
Age-adjusted1.001.291.140.980.800.49–1.290.09
Multivariate-adjustedb1.001.311.150.990.790.49–1.280.11
Multivariate-adjustedc1.001.381.271.161.060.63–1.780.85
Vitamin E from food and supplements
No. of cases4531373452
Intake (IU/day)4.15.57.018.4209.5
RR
Age-adjusted1.000.660.750.721.010.67–1.520.12
Multivariate-adjustedb1.000.670.760.741.000.66–1.490.17
Multivariate-adjustedc1.000.650.770.781.080.72–1.640.06
Vitamin E, food only
No. of cases3839463937
Intake (IU/day)3.95.05.86.78.5
RR
Age-adjusted1.000.991.150.930.840.53–1.340.32
Multivariate-adjustedb1.000.981.130.900.810.51–1.290.29
Multivariate-adjustedc1.000.961.110.890.890.55–1.430.53
  • a Values for intake are medians for each quintile.

  • b The multivariate models included age (5-year categories), total energy (quintiles), length of follow-up (seven periods), geographic region (Northeast, Midwest, South, California), cigarette smoking (never, past, present smoking of 1–14 cigarettes and≥ 15 cigarettes/day), and height (<62 inches, ≥62 to <64 inches,≥ 64 to <66 inches, ≥66 to <68 inches, or ≥68 inches).

  • c Additional adjustment for quintiles of saturated and trans unsaturated fats.

  • d Q5 95% CI = 95% CIs for quintile 5 RRs.

  • e Ps are two-sided (Wald’s test).