Table 4

The PGE2 levels after 2 or 4 weeks of ibuprofen/placebo treatment, expressed as percent of the baseline values (100 × ((PGE2)posttreatment/(PGE2)baseline))

Ibuprofen dose (mg/day)After 2 wk of treatmentAfter 4 wk of treatment
0 (placebo)78 ± 5269 ± 78
30045 ± 30a51 ± 28
60059 ± 2660 ± 46
  • a Changes in logarithmically transformed PGE2 levels were significantly different from those after placebo treatment (see data analysis section for details); P = 0.033.