Table 6

Multivariate-adjusteda mean percent breast density (95% CI) by categories of food and supplement intakes of Vitamins C, E, and B12

Vitamin intakeMenopausal statusCategory of intakebPtrendc
1234
Vitamin C (mg)Pred
Food only394240400.99
(32–50)(35–49)(37–47)(33–47)
Supplement only373943420.02
(32–43)(32–46)(37–50)(36–49)
Poste
Food only323331310.22
(30–35)(30–35)(29–34)(29–33)
Supplement only313332320.98
(29–33)(31–36)(29–34)(29–34)
Vitamin E (mg TE)Pred
Food only383842440.12
(32–45)(32–45)(35–48)(37–52)
Supplement only394240430.31
(32–45)(35–49)(33–46)(35–50)
Poste
Food only323331310.54
(29–35)(31–35)(29–33)(29–34)
Supplement only313233320.31
(29–33)(30–35)(30–35)(30–35)
Vitamin B12 (mg)Pred
Food only443939420.55
(36–51)(33–45)(32–46)(35–48)
Supplement only394242410.55
(33–45)(35–39)(35–50)(34–48)
Poste
Food only313133310.48
(29–34)(29–33)(30–36)(29–34)
Supplement only323132340.05
(30–34)(29–33)(29–34)(31–36)
  • a All analyses are adjusted for caloric intake, age, age2, body mass index, WHR, physical activity, age at menarche, age at first birth and number of births combined, self-reported alcohol intake, smoking, family history of breast cancer, hormone replacement usage (postmenopausal women), and oral contraceptive usage (premenopausal women).

  • b For food source, categories are quartiles. For supplement use, non-users make up category 1. Categories 2–4 are tertiles of supplement intake.

  • c Test for trend is an F test of the linear contrast.

  • d n = 283.

  • e n = 1225.