Table 3

Adjusted ORs for potential joint effect of CYP1B1 genotype with selected risk factors, Shanghai Breast Cancer Study, 1996–1998

Risk factorsCYP1B1 Val/Val + Val/LeuCYP1B1 Leu/Leu
Case/controlOR (95% CI)aCase/controlOR (95% CI)a
Ever diagnosed with breast fibroadenoma
No123/1651.045/272.4 (1.4–4.1)
Yes15/63.2 (1.2–8.6)3/22.1 (0.3–13.2)
Physical activity
High24/531.013/93.5 (1.3–9.5)
Low114/1182.1 (1.2–3.6)35/203.8 (1.8–7.9)
Age at first live birth (by median)b
≤26 years59/931.025/162.6 (1.3–5.3)
>26 years74/721.5 (1.0–2.5)21/112.8 (1.3–6.3)
  • a With the exception of the variables under evaluation, ORs were adjusted for the other two variables listed in the table.

  • b Among parous women.