Table 2

Associations of CYP1B1 genotype with breast cancer risk, Shanghai Breast Cancer Study, 1996–1998

CYP1B1 genotypeNo. of cases (n = 186)No. of controls (n = 200)Unadjusted OR (95% CI)Adjusteda OR (95% CI)
All study participants
Val/Val 37441.01.0
Val/Leu 1011270.9 (0.6–1.6)1.0 (0.6–1.7)
Leu/Leu 48292.0 (1.0–3.7)2.3 (1.2–4.3)
Premenopausal women
Val/Val 26261.01.0
Val/Leu 68780.9 (0.5–1.6)1.0 (0.5–1.9)
Leu/Leu 27171.6 (0.7–3.6)1.9 (0.8–4.3)
Postmenopausal women
Val/Val 11181.01.0
Val/Leu 32491.1 (0.4–2.6)1.1 (0.4–2.6)
Leu/Leu 21122.9 (1.0–8.0)3.1 (1.0–9.1)
  • a Adjusted for prior history of breast fibroadenoma, physical activity, and age at first pregnancy.