Table 5

Sensitivity analysis to examine potential influence of cachexia on OR estimates; ORs and 95% CIs for total PCB concentration in serum for pancreatic cancer cases and controls, San Francisco Bay Area, CA, 1996–1998a

Total PCBs (ng/g lipid)No bioconcentration in cases10% bioconcentration in cases25% bioconcentration in cases40% bioconcentration in cases
ORb95% CIP trendORb95% CIP trendORb95% CIP trendORb95% CIP trend
<0.001c0.007c0.16c0.61c
<1851.01.01.01.0
185–3601.30.6–2.81.20.6–2.40.70.4–1.50.70.4–1.4
≥3604.21.9–9.43.11.4–7.01.90.9–4.20.90.4–2.0
Continuousd1.0031.001–1.004<0.0011.0021.001–1.0040.0041.0011.000–1.0030.071.0000.999–1.0020.88
  • a Based on models assuming 0, 10, 25, and 40% bioconcentration in cases.

  • b All models adjusted for age interval (four categories), sex, and race.

  • c P value for categorical trend test.

  • d OR for each ng/g increase in PCB concentration.