Table 1

Urinary excretion of BBIa

Subject no.Dose (CIU)Baseline BBI (ng/mg)Time to peak excretion (h)Peak BBI (ng/mg)Increase (ng/mg)Percentage increase
2040012510621497399
2140024.3661.637.3154
2280010.637968.4642
238001.85418.416.6895
  • a BBI measurements were recorded as nanograms of BBI per milligram of creatinine using the inhibitory ELISA technique described in “Materials and Methods.” Normalization to milligrams of creatinine was performed to account for variable urine concentrations.