Table 4

Relative risk of having a large tumor (≥2 cm) or axillary-lymph-node involvement among cases, according to plasma organochlorine concentrations

PesticidesTertile limitsaTumor sizeLymph-node involvement
≥2 cm/<2 cmORb (95% CI)+/−ORb (95% CI)
β-HCH12.7<49/461.0042/491.00
12.7–18.9<33/620.65 (0.34–1.25)27/540.89 (0.44–1.79)
≥18.960/492.25 (1.12–4.51)49/522.03 (0.98–4.19)
p,p′-DDE250.0<42/551.0032/571.00
250.0–495.3<45/431.39 (0.74–2.62)38/432.06 (1.02–4.15)
≥495.355/591.64 (0.87–3.08)48/552.91 (1.43–5.91)
p,p′-DDT7.2<46/581.0040/571.00
7.2–11.8<44/441.43 (0.77–2.64)36/431.31 (0.68–2.53)
≥11.852/551.59 (0.84–3.03)42/551.51 (0.77–2.95)
Oxychlordane10.0<43/391.0037/461.00
10.0–13.7<46/620.99 (0.52–1.89)35/571.12 (0.56–2.24)
≥13.753/561.67 (0.81–3.44)46/522.34 (1.10–4.97)
trans-Nonachlor12.6<37/441.0034/411.00
12.6–17.9<54/641.52 (0.80–2.89)43/651.32 (0.66–2.63)
≥17.951/492.27 (1.11–4.65)41/491.95 (0.92–4.15)
PCB-15343.0<38/451.0032/431.00
43.0–61.7<51/521.39 (0.73–2.64)38/591.22 (0.61–2.43)
≥61.753/601.49 (0.77–2.86)48/532.12 (1.05–4.30)
  • a Organochlorine concentrations are divided in tertiles according to the distribution among the 526 controls (μg/kg, lipid basis).

  • b ORs are adjusted for age, region of residence, BMI, time separating blood sampling from surgery, breast feeding duration, and number of fertile years.