Table 3

Relative risk of breast cancer according to plasma organochlorine concentrations

OrganochlorinesQuintile limitsaNo. of womenbControls used in OR calculations
Hospital OR (95% CI)cPopulation OR (95% CI)d
β-HCH10.2<69/49/551.001.00
10.2–13.6<51/42/630.71 (0.38–1.33)0.60 (0.35–1.01)
13.6–17.2<60/34/700.85 (0.44–1.62)0.62 (0.37–1.04)
17.2–22.6<65/51/540.71 (0.38–1.32)0.86 (0.50–1.49)
≥22.669/42/630.83 (0.43–1.61)0.80 (0.47–1.35)
p,p′-DDE184.4<67/44/611.001.00
184.4–282.5<52/41/630.85 (0.45–1.59)0.75 (0.45–1.25)
282.5–427.8<56/57/470.66 (0.37–1.19)1.06 (0.62–1.79)
427.8–680.0<67/36/691.54 (0.81–2.95)0.86 (0.52–1.42)
≥680.072/40/651.36 (0.71–2.63)1.00 (0.60–1.67)
p,p′-DDT6.0<79/49/551.001.00
6.0–7.9<52/44/620.85 (0.47–1.54)0.57 (0.34–0.95)
 7.9–10.6<50/36/681.06 (0.57–1.98)0.50 (0.30–0.84)
10.6–15.0<63/44/601.07 (0.59–1.94)0.71 (0.43–1.19)
≥15.070/45/601.37 (0.73–2.56)0.81 (0.48–1.37)
Oxychlordane8.4<53/43/611.001.00
 8.4–10.6<62/42/631.10 (0.58–2.09)1.09 (0.65–1.82)
10.6–12.6<60/39/660.96 (0.49–1.88)1.00 (0.59–1.69)
12.6–16.3<70/44/610.81 (0.41–1.61)1.26 (0.74–2.16)
≥16.369/50/540.55 (0.27–1.13)1.47 (0.83–2.62)
trans-Nonachlor10.6<52/48/561.001.00
<10.6–13.5  56/36/691.25 (0.64–2.42)0.82 (0.49–1.40)
13.5–16.9<93/44/601.46 (0.77–2.76)1.53 (0.91–2.59)
16.9–20.7<46/41/650.59 (0.29–1.20)0.69 (0.39–1.23)
≥20.767/49/550.74 (0.38–1.47)1.20 (0.68–2.13)
PCB-15336.3<51/47/571.001.00
36.3–46.6<66/43/631.02 (0.54–1.94)1.12 (0.66–1.88)
46.6–57.1<56/39/640.99 (0.50–1.93)0.94 (0.55–1.62)
57.1–69.3<61/51/540.64 (0.33–1.23)1.18 (0.68–2.05)
≥69.380/38/671.07 (0.54–2.12)1.28 (0.74–2.19)
  • a Organochlorine concentrations are divided in quintiles according to the distribution among the 526 controls (μg/kg, lipid basis).

  • b Cases/hospital controls/population controls.

  • c OR adjusted for age, region of residence, BMI, breast feeding duration, age at first child, number of fertile years, family history of breast cancer, and history of benign breast disease.

  • d OR adjusted for age and region of residence.