Table 2

Levels of pesticides or their metabolites and PCB congeners measured among breast cancer cases and controlsa

Pesticide or pesticide metabolite/PCB congener (Ballschmiter no. Wolff groupb)ncMean concentration in serum (ng/g serum)PdMean lipid-adjusted concentration (ng/g lipid)PdOR by Q,e relative to lowest Q
ControlsCasesControlsCasesQ2Q3Q4
B-HCCH1440.4140.3810.3463.460.00.451.00.70.7
Heptachlor epoxide1440.0550.0450.078.57.10.101.51.81.0
Oxychlordane1430.0720.0640.1610.910.00.231.01.00.9
Trans-nonachlor1450.0760.0650.0411.710.40.101.00.91.0
p-p′-DDE1448.237.930.76126012300.840.71.01.2
p,p′-DDT1460.8980.760.20137.7119.50.270.20.50.3
3,3′,4,4′,5-penta (126-2A)1421.1 × 10−31.1 × 10−30.700.1640.1660.861.11.31.1
3,3′,4,4′,5,5-hexa (169-2A)1440.5 × 10−30.5 × 10−30.140.0840.0800.300.91.10.6
2,4,4′,5-tetra (74-2A)1340.1830.1680.1128.727.00.300.90.60.6
2,2′,4,4′,5-penta (99-3)1420.1890.1630.0628.825.70.120.50.60.6
2,3′4,4′5-penta (118-2A)1410.3420.3220.2852.850.70.460.80.40.6
2,3,3′,4,4′-penta (105-2A)1430.0730.0710.6711.211.10.960.90.51.0
2,2′,3,4′,5,5′-hexa (146-3*)1410.1510.1370.0823.421.80.230.80.60.6
2,2′,4,4′,5,5′-hexa (153-3)1431.261.150.06195.6183.40.210.90.70.6
Several (138-158-not classified)1430.9070.8350.11140.0132.80.320.50.70.6
2,3′,4,4′,5,5′-hexa (167-2A)1390.0430.0400.166.76.40.450.80.60.7
2,3,3′,4,4′5-hexa (156-2A)1420.1070.0970.0716.615.50.230.80.80.5
2,3,3′,4,4′,5′-hexa (157-2A*)1350.0240.0230.673.73.80.900.80.90.6
2,2′,3,3′,5,5′,6-hepta (178-3)1340.0540.0530.828.58.40.860.70.70.5
2,2′,3,4′,5,5′,6-hepta (187-1B)1420.2470.2370.6238.237.20.730.70.80.5
2,2′,3,4,4′,5′,6-hepta (183-3)1420.1070.1030.7116.416.20.870.70.70.4
2,2′,3,3′,4,5,6-hepta (177-1B)1380.080.070.4312.412.10.801.00.80.6
2,2′,3,3′,4,5,5′-hepta (172-3*)1350.0440.0400.096.936.410.220.60.90.5
2,2′,3,4,4′,5,5′-hepta (180-3)1420.7420.6690.04115.8107.70.180.60.90.5
2,2′,3,3′,4,4′,5-hepta (170-2B)1370.3350.3060.0752.049.20.320.41.00.5
2,3,3′,4,4′,5,5′-hepta (189-2A*)1340.0170.0180.282.793.020.180.40.81.0
2,2′3,3′,4,5,5′,6′-octa (201-1B)1380.0940.0880.2414.714.00.480.60.90.5
Several (196-203-not classified)1410.1110.1020.1117.316.30.280.60.90.5
2,2′,3,4,4′,5,6-octa (195-3*)1290.0350.0300.075.434.840.171.20.90.6
2,2′,3,3′,4,4′,5,5′-octa (194-3*)1410.1160.1070.1118.317.20.280.81.30.6
2,2′,3,3′,4,4′,5,5′,6-nona (206-3*)1290.0360.0330.205.615.200.311.10.70.8
2,2′,3,3′,4,4′,5,5′,6,6′-deca (209-3*)1320.0290.0250.044.523.970.060.70.50.5
PCB group 1B1430.4190.3960.4065.062.60.560.60.60.5
PCB group 2A1470.770.730.26120.0116.30.50.80.60.6
PCB group 2B1370.3350.3060.0752.049.20.320.41.00.5
Total PCB group 21471.091.030.27169.8165.20.590.90.80.8
PCB group 31432.642.390.04427.1398.70.180.70.80.6
Total PCBs1475.094.760.18806.6776.10.470.60.80.5
  • a Only compounds with >90% of samples above LD are included.

  • b PCB congeners were grouped according to a classification system developed by Wolff et al. (1997), as described in “Materials and Methods.” For those compounds that had not been classified previously by this scheme in the published literature, the group was inferred by the authors and designated with an

  • * .

  • c No. of pairs in which both members had valid analytical results, including results below the limit of detection.

  • d P calculated from paired t test.

  • e Q, quartile; Q1 OR = 1.00.