Table 5

ORs for lipid-adjusted total PCBs and breast cancer, stratified by BMI

	Cases	Controls	OR^a (95% CI)	OR^b (95% CI)
Lowest third of BMI^c
African-Americans
Total PCBs^d
<0.312	29	24	Referent	Referent
0.312 to <0.54	38	30	1.13 (0.54–2.40)	1.22 (0.54–2.73)
≥0.54	35	33	0.90 (0.38–2.11)	0.82 (0.32–2.08)
Whites
Total PCBs
<0.265	54	36	Referent	Referent
0.265 to <0.417	69	35	1.50 (0.82–2.74)	1.28 (0.67–2.42)
≥0.417	49	57	0.90 (0.47–1.71)	0.72 (0.36–1.46)
Middle third of BMI
African-Americans
Total PCBs
<0.312	24	29	Referent	Referent
0.312 to <0.54	32	31	1.31 (0.59–2.90)	1.11 (0.48–2.60)
≥0.54	44	27	1.65 (0.63–4.36)	2.51 (0.85–7.45)
Whites
Total PCBs
<0.265	53	38	Referent	Referent
0.265 to <0.417	50	47	0.83 (0.45–1.52)	0.81 (0.41–1.62)
≥0.417	56	44	0.95 (0.49–1.85)	0.77 (0.36–1.65)
Highest third of BMI
African-Americans
Total PCBs
<0.312	23	33	Referent	Referent
0.312 to <0.54	25	28	2.09 (0.87–5.05)	2.20 (0.86–5.63)
≥0.54	33	27	3.83 (1.42–10.34)	4.92 (1.63–14.83)
Whites
Total PCBs
<0.265	39	55	Referent	Referent
0.265 to <0.417	52	45	1.79 (0.99–3.25)	1.85 (0.97–3.54)
≥0.417	29	29	1.79 (0.85–3.79)	1.82 (0.79–4.20)

^a Adjusted for age, age-squared.
^b Adjusted for age, age-squared, menopausal status, parity/lactation, HRT use, and income.
^c Cutpoints for BMI (kg/m²) are race specific: <28.16, 28.16 to <34.2, and≥ 34.2 in African-Americans; <23.50, 23.50 to <27.94, and ≥27.94 in whites.
^d Total PCBs in μg/g lipid. Cutpoints for total PCBs are race specific, based upon controls.