Table 5

ORs for lipid-adjusted total PCBs and breast cancer, stratified by BMI

CasesControlsORa (95% CI)ORb (95% CI)
Lowest third of BMIc
African-Americans
Total PCBsd
<0.3122924ReferentReferent
0.312 to <0.5438301.13 (0.54–2.40)1.22 (0.54–2.73)
≥0.5435330.90 (0.38–2.11)0.82 (0.32–2.08)
Whites
Total PCBs
<0.2655436ReferentReferent
0.265 to <0.41769351.50 (0.82–2.74)1.28 (0.67–2.42)
≥0.41749570.90 (0.47–1.71)0.72 (0.36–1.46)
Middle third of BMI
African-Americans
Total PCBs
<0.3122429ReferentReferent
0.312 to <0.5432311.31 (0.59–2.90)1.11 (0.48–2.60)
≥0.5444271.65 (0.63–4.36)2.51 (0.85–7.45)
Whites
Total PCBs
<0.2655338ReferentReferent
0.265 to <0.41750470.83 (0.45–1.52)0.81 (0.41–1.62)
≥0.41756440.95 (0.49–1.85)0.77 (0.36–1.65)
Highest third of BMI
African-Americans
Total PCBs
<0.3122333ReferentReferent
0.312 to <0.5425282.09 (0.87–5.05)2.20 (0.86–5.63)
≥0.5433273.83 (1.42–10.34)4.92 (1.63–14.83)
Whites
Total PCBs
<0.2653955ReferentReferent
0.265 to <0.41752451.79 (0.99–3.25)1.85 (0.97–3.54)
≥0.41729291.79 (0.85–3.79)1.82 (0.79–4.20)
  • a Adjusted for age, age-squared.

  • b Adjusted for age, age-squared, menopausal status, parity/lactation, HRT use, and income.

  • c Cutpoints for BMI (kg/m2) are race specific: <28.16, 28.16 to <34.2, and≥ 34.2 in African-Americans; <23.50, 23.50 to <27.94, and ≥27.94 in whites.

  • d Total PCBs in μg/g lipid. Cutpoints for total PCBs are race specific, based upon controls.