Table 4

ORs for lipid-adjusted DDE and breast cancer, stratified by BMI

Case no.Control no.ORa (95% CI)ORb (95% CI)
Lowest third of BMIc
African-Americans
DDEd
<0.713735ReferentReferent
0.71 to <1.829211.31 (0.62–2.73)1.25 (0.57–2.73)
≥1.836311.14 (0.55–2.35)1.54 (0.58–3.49)
Whites
DDE
<0.308951ReferentReferent
0.30 to <0.6638400.61 (0.34–1.08)0.69 (0.37–1.28)
≥0.5445370.91 (0.50–1.64)0.99 (0.52–1.88)
Middle third of BMI
African-Americans
DDE
<0.712729ReferentReferent
0.71 to <1.835311.13 (0.51–2.49)0.80 (0.33–1.92)
≥1.838271.17 (0.49–2.79)1.07 (0.41–2.76)
Whites
DDE
<0.304843ReferentReferent
0.30 to <0.6659511.15 (0.64–2.05)0.91 (0.48–1.74)
≥0.5452351.53 (0.81–2.91)1.29 (0.63–2.64)
Highest third of BMI
African-Americans
DDE
<0.712123ReferentReferent
0.71 to <1.823340.98 (0.41–2.34)0.98 (0.37–2.55)
≥1.837311.86 (0.77–4.49)1.90 (0.71–5.09)
Whites
DDE
<0.303535ReferentReferent
0.30 to <0.6648361.30 (0.68–2.50)1.66 (0.81–3.39)
≥0.5437580.62 (0.32–1.19)0.89 (0.43–1.82)
  • a Adjusted for age and age-squared.

  • b Adjusted for age, age-squared, menopausal status, parity/lactation, HRT use, and income.

  • c Cutpoints for BMI (kg/m2) are race specific: <28.16, 28.16 to <34.2, and≥ 34.2 in African-Americans; <23.50, 23.50 to <27.94, and ≥27.94 in whites.

  • d p,p′-DDE in μg/g lipid. Cutpoints for DDE are race specific, based upon controls.