Table 3

ORs for lipid-adjusted DDE and PCBs and breast cancer, stratified by parity and history of breastfeeding

CasesControlsORa (95% CI)ORb (95% CI)
Nulliparous
DDEc
<0.3944125ReferentReferent
0.394 to <1.04436231.28 (0.59–2.78)1.24 (0.54–2.82)
≥1.04435171.87 (0.67–5.20)1.48 (0.49–4.46)
Total PCBsd
<0.2833725ReferentReferent
0.283 to <0.46939211.51 (0.69–3.33)2.06 (0.88–4.85)
≥0.46936191.74 (0.67–4.54)1.62 (0.57–4.58)
Parous, never breastfed
DDE
<0.394131102ReferentReferent
0.394 to <1.0441221230.86 (0.59–1.26)0.96 (0.65–1.42)
≥1.0441341111.07 (0.91–2.15)1.23 (0.80–1.89)
Total PCBs
<0.283115112ReferentReferent
0.283 to <0.4691591251.51 (1.04–2.20)1.50 (1.01–2.23)
≥0.469113991.40 (0.91–2.15)1.30 (0.82–2.06)
Parous, ever breastfed
DDE
<0.39410293ReferentReferent
0.394 to <1.04473730.94 (0.60–1.48)1.16 (0.70–1.90)
≥1.04474920.71 (0.41–1.21)0.80 (0.45–1.44)
Total PCBs
<0.2838782ReferentReferent
0.283 to <0.46968740.92 (0.58–1.47)0.90 (0.55–1.48)
≥0.469941020.95 (0.57–1.57)0.84 (0.49–1.44)
  • a Adjusted for age, age-squared, and race.

  • b Adjusted for age, age-squared, race, menopausal status, BMI, HRT use, and income.

  • c p,p′-DDE in μg/g lipid.

  • d Total PCBs in μg/g lipid.