Table 2

Frequency of p53 genotypes among controls and histological types of lung cancer

nArg/Arg, n (%)Arg/Pro, n (%)Pro/Pro, n (%)
Controls510237 (46.47)212 (41.57)61 (11.96)
Hystological types
All482212 (43.98)204 (42.32)66 (13.69)
Adenocarcinoma24496 (39.34)108 (44.26)40 (16.39)a
Squamous cell13373 (54.89)44 (33.08)16 (12.03)
Large cell2611 (42.31)13 (50)2 (7.69)
Small cell259 (36)13 (52)3 (12)
Broncho-alveolar105 (50)4 (40)1 (1)
Mixed167 (43.75)8 (50)1 (6.25)
>1 primary lung cancer216 (28.57)12 (57.14)3 (14.29)
  • a P = 0.03 for comparison of p53 Pro/Pro genotype with p53 Arg/Arg genotype between adenocarcinoma cases and controls.