Table 2

Time course of flow cytometric DNA ploidy in serial bladder washings by treatment assignment

NDNA aneuploidOdds ratioa (95% CI)
n(%)
Baseline
Control4525(55.6)
Fenretinide4834(70.8)
4 Months
Control4636(78.3)
Fenretinide4330(69.8)
8 Months
Control4726(55.3)
Fenretinide4223(54.8)
12 Months
Control4318(41.9)
Fenretinide4723(48.9)1.16 (0.44–3.07)
16 Months
Control4310(23.3)
Fenretinide4215(35.7)
20 Months
Control4213(31.0)
Fenretinide3918(46.2)
24 Months
Control4121(51.2)
Fenretinide4117(41.5)0.62 (0.21–1.77)
28 Months
Control3815(39.5)
Fenretinide4221(50.0)
32 Months
Control3217(53.1)
Fenretinide3820(52.6)
36 Months
Control3616(44.4)
Fenretinide4123(56.1)1.69 (0.58–4.94)
  • a Odds ratio and 95% confidence interval (CI) adjusted for baseline DNA ploidy.