Table 3

Association of childhood ALL with maternal occupational exposures to hydrocarbons by duration of time of exposure

AnytimePreconceptionDuring pregnancyPostnatal
Case/ControlOR (95% CI)aCase/ControlOR (95% CI)aCase/ControlOR (95% CI)aCase/ControlOR (95% CI)a
Solvents, degreasers, or cleaning agents
 None1704/18721.01743/19211.01768/19331.01749/18921.0
 ≤Median88/541.8 (1.3–2.6)56/292.1 (1.3–3.4)37/231.9 (1.1–3.2)58/451.4 (1.0–2.1)
 >Median45/530.9 (0.6–1.4)37/291.4 (0.8–2.3)31/231.3 (0.7–2.2)29/420.7 (0.4–1.1)
 Test for trend (P)0.24<0.010.070.63
Plastic materials
 None1811/19721.01822/19761.01825/19791.01816/19751.0
 ≤Median14/72.3 (0.9–6.2)7/51.6 (0.5–5.4)4/31.5 (0.3–7.0)17/53.0 (1.1–8.2)
 >Median15/62.3(0.9–6.0)11/41.6 (0.8–8.3)11/33.2 (0.9–11.7)7/51.5 (0.5–4.7)
 Test for trend (P)0.030.090.070.09
Paints or thinners
 None1673/18191.01730/18811.01739/18921.01722/18481.0
 ≤Median74/671.3 (0.9–1.8)54/351.8 (1.2–2.9)45/301.8 (1.1–3.0)53/521.2 (0.8–1.8)
 >Median83/671.4 (1.0–1.9)43/351.4 (0.9–2.2)43/291.5 (0.9–2.4)52/511.1 (0.7–1.6)
 Test for trend (P)0.040.020.010.56
Oils or coal products
 None1738/18791.01774/19181.01794/19261.01770/19011.0
 ≤Median57/511.2 (0.8–1.8)32/311.1 (0.6–1.7)24/170.9 (0.5–1.6)33/400.9 (0.5–1.4)
 >Median43/500.9 (0.6–1.4)31/311.1 (0.6–1.8)19/270.7 (0.4–1.3)34/390.9 (0.6–1.4)
 Test for trend (P)0.100.770.220.49
Other
 None1658/18091.01718/18751.01746/19001.01709/18521.0
 ≤Median105/861.3 (1.0–1.8)72/521.5 (1.0–2.2)44/391.3 (0.9–2.1)71/631.3 (0.9–1.8)
 >Median74/841.0 (0.7–1.4)46/511.1 (0.7–1.7)46/391.3 (0.8–2.0)56/631.0 (0.7–1.5)
 Test for trend (P)0.400.140.110.54
  • a ORs were adjusted for maternal education, race, and family income.