Table 2

Age-specific cumulative risk of breast cancer for the Australian population and estimated average risk for carriers of a BRCA1 or BRCA2 mutation

Age (yr)
40506070
Australian population (Ref. 15 )0.82.54.97.5
ABCFS (BRCA1 or BRCA2)
 Repeated sampling6 (0–17)a10 (0–24)28 (11–52)36 (15–65)
 Maximum likelihood8 (0–20)10 (0–24)31 (7–56)40 (16–64)
BCLC families
BRCA1 (Ref. 3 )18 (0–35)49 (28–64)64 (43–77)71 (53–82)
BRCA2 (Ref. 5 )12 (0–24)28 (9–44)48 (22–65)84 (43–95)
  • a Values are percentage risks; values in parentheses are 95% CIs.