Table 3

ORs for the Cys/Cys genotype of hOGG1 Ser326Cys polymorphism versus the other genotypes combined and those stratified by smoking dosage

GenotypeNo. of cases/controlsCrudeAdjusted for age and smoking habits
OR95% CIPOR95% CIP
Total
Ser/Ser+ Ser/Cys200/1701.001.00
Cys/Cys41/271.290.76–2.190.3431.710.92–3.190.091
Squamous cell carcinoma
Ser/Ser+ Ser/Cys94/1701.001.00
Cys/Cys24/271.610.88–2.940.1243.011.33–6.830.008a
Small cell carcinoma
Ser/Ser+ Ser/Cys26/1701.001.00
Cys/Cys2/270.480.11–2.160.3420.720.14–3.660.691
Adenocarcinoma
Ser/Ser+ Ser/Cys65/1701.001.00
Cys/Cys13/271.260.61–2.590.5311.580.68–3.650.290
Nonadenocarcinoma
Ser/Ser+ Ser/Cys130/1701.001.00
Cys/Cys28/271.360.76–2.410.3002.181.05–4.540.037a
Adjusted for age
OR95% CI P
Cigarette-years <800
Ser/Ser+ Ser/Cys62/1001.001.00
Cys/Cys16/201.290.62–2.680.4941.160.55–2.460.697
Cigarette-years ≥800
Ser/Ser + Ser/Cys138/491.001.00
Cys/Cys25/42.220.74–6.700.1572.330.77–7.090.137
  • a P < 0.05.