Table 3

Geometric meana for oral clearance of chlorzoxazone (CL; ml/min) after exclusion of a possible “outlier” or subjects who used alcohol, medications, or supplements during the previous 3 days

Exclusionsc1/c1c1/c2c2/c2Pc
nbCLnCLnCL1 vs. 31 vs. 22 vs. 3
Possible “outlier”17223.919201.113147.60.0080.420.04
Alcohol16220.618199.312155.00.040.490.12
Acetaminophen16221.718199.113146.40.010.470.06
Any medications9221.78199.18146.40.010.470.06
Supplements6276.86276.65120.80.030.990.03
  • a Adjusted for age and sex by multiple covariance analysis.

  • b Number of subjects included.

  • c Ps for differences between genotypes (1, c1/c1; 2, c1/c2; 3, c2/c2).