Table 5

p53 mutations among 243 lung cancer cases diagnosed 1980–1984 in Sweden, according to SSCP analysis and immunohistochemical staining

Low radon exposureHigh radon exposure
NonsmokerSmokerNonsmokerSmoker
Positive in SSCPNegative in SSCPPositive in SSCPNegative in SSCPPositive in SSCPNegative in SSCPPositive in SSCPNegative in SSCP
Reactivea1101326481523
Nonreactive2251349213831
Concordance0.680.610.630.60
  • a The percentage of reactive tumors according to the IHC was 28.9 among nonsmokers and 38.6 among smokers with low radon exposure, and 44.4 among nonsmokers and 49.4 among smokers with high radon exposure.