Association between organochlorine components and the risk of breast cancer by menopausal status at diagnosis and estrogen receptor status
1974 | 1989 | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lower third | Middle third | Upper third | Ptrend | Lower third | Middle third | Upper third | Ptrend | |||||||
DDE | ||||||||||||||
Premenopausal at diagnosis | 1.0 | 0.42 | 0.86 | (0.68) | 1.0 | 4.28 | 1.42 | (0.8) | ||||||
Postmenopausal at diagnosis | 1.0 | 0.75 | 0.52 | (0.003) | 1.0 | 1.57 | 0.50 | (0.15) | ||||||
Estrogen receptor-negative | 1.0 | 1.10 | 1.67 | (0.41) | 1.0 | 0.74 | 0.17 | (0.13) | ||||||
Estrogen receptor-positive | 1.0 | 0.86 | 0.80 | (0.61) | 1.0 | 2.28 | 0.59 | (0.19) | ||||||
PCB | ||||||||||||||
Premenopausal at diagnosis | 1.0 | 0.65 | 2.21 | (0.12) | 1.0 | 1.45 | 2.12 | (0.40) | ||||||
Postmenopausal at diagnosis | 1.0 | 0.67 | 0.62 | (0.10) | 1.0 | 0.83 | 0.74 | (0.44) | ||||||
Estrogen receptor-negative | 1.0 | 1.13 | 1.34 | (0.71) | 1.0 | 0.19 | 0.07 | (0.06) | ||||||
Estrogen receptor-positive | 1.0 | 0.98 | 0.83 | (0.69) | 1.0 | 0.91 | 1.19 | (0.55) |