Table 4

Association between DDE and PCBs and breast cancer risk

19741989
FifthsCasesControlsOR(95% CI)ThirdsCasesControlsOR(95% CI)
Total DDE
 Unadjusted1. <6.9362471.01. <4.3429351.0
 ng/ml2. 6.94–9.6052470.88(0.52–1.50)2. 4.35–10.5359341.80(0.97 –3.33)
3. 9.61–12.8648460.83(0.49–1.43)3. 10.54–57.1617360.53(0.24–1.17)
4. 12.87–17.7443480.70(0.40–1.22)
5. 17.75–80.3330470.50(0.27–0.89)
(Ptrend = 0.02)(Ptrend = 0.08)
 Lipid-adjusted1. <1017.1949471.01. <816.338351.0
 ng/g2. 1,017.20–1,425.3961471.24(0.72–2.13)2. 816.4–1,595.144351.18(0.65–2.13)
3. 1,425.40–1,864.5747470.96(0.55–1.67)3. 1,595.2–10,065.623350.58(0.29–1.17)
4. 1,864.58–2,446.6942470.86(0.49–1.51)
5. 2,446.70– 10,795.9136470.73(0.40–1.32)
(Ptrend = 0.13)(Ptrend = 0.15)
Total PCBs
 Unadjusted1. <2.8353471.0
 ng/ml2. 2.84–3.7156471.07(0.61–1.89)1. <1.3042341.0
3. 3.72–4.7744470.80(0.44–1.47)2. 1.31–2.1729350.65(0.33–1.30)
4. 4.78–6.2842470.75(0.42–1.34)3. 2.18–14.6334360.73(0.37–1.46)
5. 6.29–32.6040470.68(0.36–1.29)
(Ptrend = 0.16)(Ptrend = 0.56)
 Lipid-adjusted1. <394.4742471.0
 ng/g2. 394.48–558.7259471.41(0.79–2.50)1. 13.6–191.840341.0
3. 558.73–669.4641470.94(0.49–1.77)2. 191.9–333.532350.78(0.41–1.47)
4. 669.47–852.2245471.08(0.59–2.01)3. 333.6–2,007.933360.76(0.38–1.51)
5. 852.23–6,460.0448471.12(0.59–2.15)
(Ptrend = 0.44)(Ptrend = 0.60)