Table 1

Characteristics of breast cancer cases by HER-2/neu status and controls among young women <45 years of age in New Jersey, 1990–1992

HER-2/neu+ (n = 159)HER-2/neu− (n = 212)Controls (n = 462)Pa
Age at diagnosis
 23–29 years5 (3.14%)9 (4.25%)27 (5.84%)0.28
 30–34 years25 (15.72%)31 (14.62%)83 (17.97%)
 35–39 years49 (30.82%)57 (26.89%)147 (31.82%)
 40–44 years80 (50.31%)115 (54.25%)205 (44.31%)
Stage at diagnosis (%)In situ11 (6.96%)27 (13.04%)0.11
 Local77 (48.73%)104 (50.24%)
 Regional/Distant70 (44.30%)76 (36.71%)
ER status (%) 0.02
 Positive62 (44.29%)109 (59.89%)
 Borderline14 (10.00%)17 (9.34%)
 Negative64 (45.71%)56 (30.77%)
Progesterone receptor status (%)0.34
 Positive78 (56.52%)106 (59.89%)
 Borderline6 (4.34%)13 (7.34%)
 Negative54 (39.13%)58 (32.77%)
Race (%)
 White131 (82.39%)182 (85.85%)382 (82.68%)0.27
 Black16 (10.06%)24 (11.32%)48 (10.39%)
 Asian and other12 (7.55%)6 (2.83%)32 (6.93%)
Religion (%)
 Protestant52 (32.70%)70 (33.02%)154 (33.33%)0.61
 Jewish14 (8.81%)23 (10.85%)46 (9.96%)
 Catholic86 (54.09%)115 (54.25%)238 (51.52%)
 Other/None7 (4.40%)4 (1.89%)24 (5.19%)
  • a P for χ2 test. Bold, statistically significant heterogeneity.