Dietary and supplemental intake of vitamin D and breast cancer risk among white women: NHANES I Epidemiologic Follow-up Study, 1971–1975 to 1992
Breast cancer cases | Age-adjusted RR (95% CI) | Multivariate-adjusted RR (95% CI)a | ||||
---|---|---|---|---|---|---|
Dietary vitamin D | ||||||
<100 IU | 86 | 1.0 | 1.0 | |||
100–199 IU | 51 | 1.03 (0.73–1.45) | 1.05 (0.74–1.49) | |||
≥200 IU | 40 | 0.84 (0.58–1.23) | 0.85 (0.59–1.24) | |||
P for trend | P = 0.43 | P = 0.48 | ||||
Supplement use (multivitamins or single vitamin D) | ||||||
Never | 133 | 1.0 | 1.0 | |||
Weekly | 13 | 0.94 (0.53–1.65) | 0.89 (0.50–1.58) | |||
Daily | 31 | 0.93 (0.63–1.38) | 0.89 (0.60–1.32) | |||
P for trend | P = 0.69 | P = 0.52 | ||||
Vitamin D from food or supplements | ||||||
<100 IU without daily supplements | 73 | 1.0 | 1.0 | |||
100–199 IU without daily supplements | 41 | 0.98 (0.67–1.44) | 1.01 (0.69–1.49) | |||
≥200 IU or daily supplements | 63 | 0.87 (0.62–1.21) | 0.86 (0.61–1.20) | |||
P for trend | P = 0.40 | P = 0.37 |
a Adjusted for age, education, age at menarche, age at menopause, body mass index, frequency of alcohol consumption, physical activity, and calcium intake.