Table 5

Patterns of cigarette smoking (multivariate adjusteda ORs and 95% CIs) for p53+ and p53− breast cancer among women under the age of 45 years in New Jersey, 1990–1992

Controls (n = 462)p53+ cases (n = 168)p53− cases (n = 210)p53+ OR (95% CI)p53− OR (95% CI)Ratio of the ORs (95% CI)
Among ever smokers
Duration of smoking (pack-years)
 Never248811091.01.0
 <56926381.22 (0.69–2.17)1.04 (0.63–1.71)1.18 (0.63–2.21)
 5–157331281.81 (1.06–3.13)0.82 (0.48–1.40)2.23 (1.18–4.22)
 ≥167130351.41 (0.80–2.48)0.85 (0.50–1.44)1.66 (0.86–3.18)
Years of smoking
 Never248811091.01.0
 <10 years7431281.57 (0.91–2.72)0.73 (0.42–1.25)2.16 (1.14–4.12)
 10–18 years6629391.67 (0.95–2.93)1.43 (0.87–2.36)1.17 (0.63–2.17)
 ≥18 years7327341.17 (0.66–2.09)0.69 (0.41–1.17)1.71 (0.89–3.30)
Number of cigarettes/day
 Never248811091.01.0
 <105918300.99 (0.52–1.87)0.94 (0.55–1.61)1.05 (0.52–2.14)
 10–194821251.73 (0.93–3.21)1.06 (0.59–1.89)1.63 (0.82–3.26)
 ≥2010648461.65 (1.02–2.69)0.81 (0.51–1.29)2.04 (1.16–3.58)
Age started smoking
 Never248811091.01.0
 8–15 years6616190.92 (0.47–1.79)0.51 (0.27–0.95)1.81 (0.81–4.04)
 16–17 years5527291.84 (1.02–3.29)1.23 (0.71–2.12)1.49 (0.78–2.85)
 ≥18 years9244531.60 (0.98–2.60)1.00 (0.64–1.57)1.60 (0.93–2.77)
Among current smokers only
Duration of smoking (pack-years)
 Never248811091.01.0
 <165520181.48 (0.78–2.81)0.61 (0.32–1.17)2.40 (1.10–5.24)
 ≥165823251.15 (0.60–2.22)0.67 (0.36–1.25)1.72 (0.80–3.71)
Years of smoking
 Never248811091.01.0
 <18 years5120161.50 (0.75–2.99)0.74 (0.37–1.47)2.03 (0.87–4.71)
 ≥18 years6223271.17 (0.62–2.19)0.58 (0.32–1.06)2.01 (0.97–4.19)
Number of cigarettes/day
 Never248811091.01.0
 <204916161.28 (0.65–2.54)0.55 (0.28–1.08)2.35 (1.03–5.37)
 ≥206427271.32 (0.71–2.45)0.73 (0.40–1.32)1.81 (0.88–3.76)
Age started smoking
 Never248811091.01.0
 8–17 years6418230.99 (0.50–1.96)0.68 (0.37–1.25)1.47 (0.67–3.24)
 ≥18 years4925201.64 (0.88–3.06)0.61 (0.32–1.17)2.69 (1.26–5.73)
  • a Adjusted for age, race, education, alcohol use, body mass index, age at first birth, parity status, age at menarche, family history of breast cancer, prior breast biopsy, caloric intake, and electric blanket use.