Table 1

Risk of postmenopausal breast cancer associated with PCB body burden, Western New York 1986–1991

CaseControlCrude OR95% CIAdj. ORa95% CI
PCBs
Lowb70 (46)96 (50)1.01.0
Highc84 (54)95 (50)1.120.79–1.861.270.76 –2.14
Total154 (45)191 (55)
Cyp1A1 genotype
Ile:Ile 127 (83)168 (88)1.01.0
Ile:Val or Val:Val27 (17)23 (12)1.560.86–2.851.790.91 –3.55
Total154 (45)191 (55)
  • a ORs adjusted for age, education, serum lipids, age at menopause, family history of breast cancer, age at first birth, parity, duration of lactation, body mass index, and smoking status.

  • b 0.75–3.72 ng/g of serum.

  • c 3.73–19.04 ng/g of serum.